Translational Challenge
Motor Neuron Disease
Our vision is a world where motor neuron disease (MND) is preventable and treatable.
Motor neuron disease (MND) affects the nerves in the brain and spinal cord that help tell muscles what to do.
We still know far too little about how to predict the onset or progression of MND, or to develop treatments or cures.
We want to use our expertise in early-stage science to progress discoveries that can intervene early, provide better treatments and improve the quality of life for those living with MND.
What do we want to achieve?
- Contribute to making medicines and diagnostics
- Detect and diagnose MND earlier
- Connect experts across MND research
- Unblock barriers that keep scientific discoveries from reaching patients
- Listen and learn from people living with MND
Discover expert and community-driven insights
MND Insights report
Our MND Insights Group ensures those affected by MND shape research priorities. This report contains the key findings from workshops and a community-wide survey.
MND biomarker roadmap report
We hosted a roundtable with MND biomarker experts to tackle key challenges and explore solutions. This report shares insights to advance the field.
How you can work with us
We partner and invest in the work of academics, charities, healthcare professionals and industry to:
Analyse patient data to predict those at risk of developing MND
Uncover new therapies for MND, faster
Identify novel biomarkers to accelerate diagnosis and measure disease progression
Develop technology to improve the day-to-day quality of life for those living with MND
Some of our partnerships and initiatives
Validating therapeutic targets for motor neuron disease
We have teamed up with King’s College London to launch the MND STaR (Solution for Motor Neuron Disease Target Validation and Research) programme.
Advancing ALS/MND prognosis, monitoring, and drug development
We are collaborating with the ALS Therapy Development Institute (ALS TDI) to identify and validate biomarkers for ALS/MND.
Establishing a target product profile for MND
Our target product profile will act as a blueprint to guide the development of treatments for MND.
The MND Insights Group and community surveys
Uncovering the most important research questions and urgently address the needs of MND research, working with real experts who live with the condition.
Learn about about our work in dementia and other neurodegenerative conditions
Who to contact
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Paul Wright
Read bio: Paul Wright
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Yaa Adjei
Read bio: Yaa Adjei
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Roger Barker
Read bio: Roger Barker
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Derek Sheader
Read bio: Derek Sheader
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£76M investment backing into potential MND treatment, underlines benefit of charity funding
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News releasesNew partnership aims to develop clinical tools for motor neuron disease prognosis, monitoring, and drug development
See our other Translational Challenges
Chronic Respiratory Infection
Our vision is improved quality of life for those living with cystic fibrosis and bronchiectasis.
Global Health
Our vision is a world with affordable and accessible solutions to better understand, treat, and prevent infectious diseases.
Rare Disease
Our vision is an ecosystem working together to get discoveries and treatments to rare disease patients faster.
Childhood Cancer
Our vision is to drive life-changing innovations for children with cancer.
Contact us
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